生物炭对土壤中抗生素抗性基因的阻控潜力及机制研究进展.docx

生物炭对土壤中抗生素抗性基因的阻控潜力及机制研究进展
Title:ResearchProgressontheInhibitionPotentialandMechanismsofBiocharonAntibioticResistanceGenesinSoil
Abstract:
Antibioticresistancehasbecomeasignificantglobalconcernduetoitspotentialadverseeffectsonpublichealthandtheenvironment.Soilplaysacrucialroleinthespreadofantibioticresistancegenes(ARGs)duetothewidespreaduseofantibioticsinagriculture.Biochar,acarbon-richmaterialderivedfromthepyrolysisofbiomass,hasemergedasapotentialtooltomitigateantibioticresistanceinsoil.ThispaperreviewstherecentresearchprogressontheinhibitionpotentialandmechanismsofbiocharonARGsinsoil.Thepotentialuseofbiocharasapromisingstrategyformanagingantibioticresistanceinagriculturalecosystemsisdiscussed.
1.Introduction:
1.1Antibioticresistanceanditsenvironmentalimplications
1.2Biocharasapotentialtoolformanagingantibioticresistance
2.InhibitionpotentialofbiocharonARGsinsoil:
2.1FieldstudiesdemonstratingthereductionofARGsbybiochar
2.2Lab-scaleexperimentsinvestigatingtheefficacyofbiocharonARGs
2.3FactorsinfluencingtheinhibitionpotentialofbiocharonARGs
3.Mechanismsunderlyingthebiochar-mediatedinhibitionofARGs:
3.1Sorptionandimmobilizationofantibioticsbybiochar
3.2Changesinmicrobialcommunitystructureanddiversity
3.3Modulationofsoilphysicochemicalpropertiesbybiochar
3.4Biochar-stimulatedbiodegradationandenzymaticactivities
4.Futurechallengesandopportunitiesforbiocharapplication:
4.1Standardizationandoptimizationofbiocharproductionandapplication
4.2Long-termeffectsandstabilityofbiocharinsoil
4.3Potentialrisksandunintendedconsequencesofbiocharuse
5.Conclusion:
TheuseofbiocharasasoilamendmentshowspromiseinreducingtheabundanceofARGsandmitigatingtheenvironmentalspreadofantibioticresistance.TheinhibitionpotentialofbiocharonARGsisattributedtoitsabilitytosorbandimmobilizeantibiotics,altermicrobialcommunitycomposition,andmodulatesoilphysicochemicalproperties.However,furtherresearchisneededtooptimizebiocharproperties,investigateitslong-termeffects,andassesspotentialrisksassociatedwithitsapp