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非小细胞肺癌晚期患者GP方案引起血糖升高的干预研究 Introduction: Non-smallcelllungcancer(NSCLC)isoneofthemostdeadlycancersthataffectspeopleworldwide.ThemajorityofpatientsarediagnosedwithadvancedstageNSCLCdisease,whichoftenresultsinpoorprognosisandhighmortality.ThetreatmentofNSCLCtypicallyinvolvesacombinationofchemotherapyandradiotherapy.However,oneofthemajorsideeffectsofthistreatmentishyperglycemia.Hyperglycemiaisaconditionwhichischaracterizedbyanabnormallyhighlevelofbloodsugaranditcanincreasetheriskofdiabeticcomplications.Therefore,itisimportanttoinvestigatethestrategiestomanagehyperglycemiainNSCLCpatients. Objective: TheobjectiveofthisstudyistoinvestigatetheinterventionstrategiestomanagehyperglycemiainNSCLCpatientswhoarereceivingchemotherapyandradiotherapy. Methodology: Thisstudyinvolvedacomprehensivereviewoftheliteraturerelatedtohyperglycemiainadvanced-stageNSCLCpatients.TheliteraturesearchwascarriedoutusingvariousdatabasesincludingPubMed,MEDLINE,andCochraneLibrary.Thesearchwasbasedonthefollowingkeywords:non-smallcelllungcancer,hyperglycemia,chemotherapy,radiotherapy,intervention,andmanagement.Inclusioncriteriafortheselectionofstudiesincludestudiesthatexploredtheeffectsofinterventionstrategies,withGPregimen,onbloodsugarlevelsinadvancedNSCLCpatientsreceivingchemotherapyandradiotherapy.Exclusioncriteriawerethestudiesthatdidnotmeetthesecriteriaofinterest. Results: SeveralstudieshavereportedthattheGPregimenhasbeenusedasapartofthechemotherapyforadvancedstageNSCLCpatients.However,theGPregimenhasbeenassociatedwithanincreasedriskofhyperglycemia.Therefore,manystudieshavetriedtoinvestigatethestrategiestoreducetheincidenceofhyperglycemiainNSCLCpatientsreceivingGPregimen.ThemosteffectiveinterventionstrategiesformanaginghyperglycemiainNSCLCpatientsinvolvedietarymodifications,lifestylemodifications,andinsulintherapy. EvidencesuggeststhatdietarymodificationscansignificantlyreducetheriskofhyperglycemiainNSCLCpatients.AlowcarbohydrateandhighproteindietmaybeaneffectiveapproachtomanaginghyperglycemiainNSCL
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